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Mediator® Phosphatidic Acid for Muscle Mass & Strength

Mediator activates the Mammalian Target of Rapamycin (mTOR) pathway to boost muscle growth when combined with exercise and adequate protein intake.  

  1. Manufactured by our parent company Chemi S.p.A
  2. Made in Patrica, Italy 
  3. Doubled lean muscle mass
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How Your Product Stands Out with Mediator

Fuel to Ramp Up Results

Phosphatidic acid (PA) is naturally found in small concentrations in muscles, where it is involved in muscle protein synthesis. By supplementing with Mediator, you can help individuals increase muscle mass, lower fat mass, improve strength, and accelerate performance in aerobic and resistance training.

3.4% increase in squat strength over placebo after 8 weeks of taking PA and exercising.  

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Organoleptic & Application Profile

Ready for Any Application

Mediator is amphiphilic and only leaves behind a slight umami taste that’s easily masked. It can be used in a variety of applications, like soft gels, powders, and bars. Since protein intake is crucial for muscle growth, coupling Mediator with a protein source in a shake or bar is ideal. We recommend taking Mediator within an hour of working out. 

Certifications & Accolades

A History of Safety

  • Clinically Researched 
  • Old Dietary Ingredient (ODI) 
  • IGEN™ Non-GMO Certified
  • Kosher Certified
  • Allergen-Free
  • Natural and Bioavailable
  • Patented

Muscle drops 3-8% per decade after the age of 30, contributing to loss of movement. 

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Studied Uses for Mediator

Sustain Active Lifestyles

Include PA in your products to support exercise-related benefits for anyone, including those counteracting age-related muscle loss.

  • Muscle Strength and Power  
  • Endurance
  • Body Composition
  • Agility
  • Hypertrophy
  • mTOR Signaling
  • Lean Body Mass

Phosphatidic Acid Background

Make Every Workout Count

This lipid messenger supports muscle growth so consumers can make the most of their workouts to see desired results.

The Mammalian Target of Rapamycin (mTOR) pathway regulates vital functions like cell growth, metabolism, and protein synthesis. PA stimulates mTOR signaling, which in turn activates muscle protein synthesis so it can efficiently take amino acids from protein and create new striated muscle.   

In one study, a group of resistance-trained subjects took 750 mg of PA daily while training for 8 weeks. The PA group saw an average gain of 5.3 pounds in lean body mass over the placebo.

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Learn More About the Muscle Builder 

Download the attachments to find out how to level up your products with Mediator. 


Mediator White Paper

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Mass & Strength Patent

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Study References

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Mediator Video

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